منابع مشابه
SnapShot: Epigenomic Assays
This SnapShot depicts key sequencing-based methods used in the analysis of epigenomes, including (1)bisulfite sequencing, (2) chromatin immunoprecipiation sequencing, (3) determination of open chromatin, and (4) 3D chromatin capture.
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Identifying and annotating distal regulatory enhancers is critical to understand the mechanisms that control gene expression and cell-type-specific activities. Next-generation sequencing techniques have provided us an exciting toolkit of genome-wide assays that can be used to predict and annotate enhancers. However, each assay comes with its own specific set of analytical needs if enhancer pred...
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This review explores the key factors that influence the optimization, routine use, and profile interpretation of the SNaPshot single-base extension (SBE) system applied to forensic single-nucleotide polymorphism (SNP) genotyping. Despite being a mainly complimentary DNA genotyping technique to routine STR profiling, use of SNaPshot is an important part of the development of SNP sets for a wide ...
متن کاملAvailability of highly sensitive troponin assays and acute coronary syndrome care: insights from the SNAPSHOT registry.
OBJECTIVES To examine differences in care and inhospital course of patients with possible acute coronary syndrome (ACS) in Australia and New Zealand based on whether a highly sensitive (hs) troponin assay was used at the hospital to which they presented. DESIGN, SETTING AND PATIENTS A snapshot study of consecutive patients presenting to hospitals in Australia and New Zealand from 14 to 27 May...
متن کاملEpigenomic profiling using microarrays.
Genes occupy only a minor fraction of genomes such as ours; however, histone and nonhistone chromosomal proteins and methylated DNA bases are distributed over both genic and nongenic regions. These widespread "epigenomic" features can be mapped and characterized by alternative applications of the same microarray technologies that have been used for conventional transcriptional profiling. Here w...
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ژورنال
عنوان ژورنال: Cell
سال: 2016
ISSN: 0092-8674
DOI: 10.1016/j.cell.2016.11.015